Zbrush 202208 Link Upd Now
ZBrush 2022.08 uses the Maxon Licensing Service. Go to your task manager (Windows) or Activity Monitor (Mac), force quit "Red Giant Service" and "Maxon License Server," then relaunch ZBrush.
For a deep dive into the specific tools that defined this era of ZBrush, you can watch the official feature presentation: zbrush 202208 link