The software doesn't have administrative permissions to "read" the license. Step 1: Run the Labcenter License Manager
(rare but known to affect some hardware ID detection in older Proteus). fix your license
Now, go ahead, fix your license, and get back to simulating that embedded design. fix your license
: If the manager is empty, click "Browse for Key File" and navigate to your original license file (often ending in .lxk ). fix your license