To make Punch-Out!! work via a USB drive on a modded Wii, you need a WBFS file.
Raw ISO files are often too large for FAT32 drives (which have a 4GB file limit). Converting to .wbfs reduces file size and allows the game to work on these drives. punchout wii rom wbfs work
You did everything right, but the game crashes. Here is the fix list. To make Punch-Out
To start this journey, your Wii must already be homebrewed with the installed. Converting to
: You must have the latest d2x cIOS installed (specifically in slots 249 and 250) to allow the Wii to read game data from the USB port.
Let me know which USB Loader you are using! Managing Wii and GameCube Backups - Wii Hacks Guide
Nintendo revived the classic NES/SNES boxing series with style, motion controls (optional), and a gorgeous cel-shaded art style. You play as Little Mac, climbing ranks to face iconic opponents like Glass Joe, King Hippo, and Mr. Sandman.